USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: BIN2_HUMAN USC-OGP 2-DE database:  BIN2_HUMAN BIN2_HUMAN General information about the entry View entry in simple text format Entry name BIN2_HUMAN Primary accession number Q9UKN4 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Bridging integrator 2; AltName: Full=Breast cancer-associated protein 1;. Gene name Name=BIN2 Synonyms=BRAP1 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0297: pI=5.12; Mw=84870 Cross-references UniProtKB/Swiss-Prot Q9UBW5; BIN2_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name BIN2_HUMAN Primary accession number Q9UBW5 Secondary accession number(s) Q86VV0 Q9NWK4 Q9UKN4 Sequence was last modified on  April 3, 2007 (version 3) Annotations were last modified on  March 15, 2017 (version 116) Name and origin of the protein Description RecName: Full=Bridging integrator 2; AltName: Full=Breast cancer-associated protein 1; Gene name Name=BIN2 Synonyms=BRAP1 Encoded on Name=BIN2; Synonyms=BRAP1 Keywords 3D-structure; Alternative splicing; Cell junction; Cell membrane; Cell projection; Coiled coil; Complete proteome; Cytoplasm; Membrane; Phosphoprotein; Polymorphism; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF146531; AAD54227.1; -; mRNA EMBL AB032698; BAA88108.1; -; mRNA EMBL AB032710; BAA88125.1; -; Genomic_DNA EMBL AK000783; BAA91376.1; ALT_SEQ; mRNA EMBL AC046135; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL BC047686; AAH47686.1; -; mRNA RefSeq NP_001276936.1; NM_001290007.1; . RefSeq NP_001276937.1; NM_001290008.1; . RefSeq NP_001276938.1; NM_001290009.1; . RefSeq NP_057377.3; NM_016293.3; . UniGene Hs.14770; -; . PDB 4AVM; X-ray; 1.91 A; A=11-245 PDB 4I1Q; X-ray; 2.53 A; A/B=20-238 PDBsum 4AVM; -; . PDBsum 4I1Q; -; . ProteinModelPortal Q9UBW5; -; . SMR Q9UBW5; -; . BioGrid 119528; 7; . IntAct Q9UBW5; 6; . STRING 9606.ENSP00000267012; -; . iPTMnet Q9UBW5; -; . PhosphoSitePlus Q9UBW5; -; . SwissPalm Q9UBW5; -; . BioMuta BIN2; -; . DMDM 143811367; -; . OGP Q9UBW5; -; . EPD Q9UBW5; -; . PaxDb Q9UBW5; -; . PeptideAtlas Q9UBW5; -; . PRIDE Q9UBW5; -; . Ensembl ENST00000267012; ENSP00000267012; ENSG00000110934; . GeneID 51411; -; . KEGG hsa:51411; -; . UCSC uc058ocp.1; human. [Q9UBW5-1]; . CTD 51411; -; . DisGeNET 51411; -; . GeneCards BIN2; -; . H-InvDB HIX0201823; -; . HGNC HGNC:1053; BIN2; . HPA HPA038666; -; . HPA HPA038667; -; . MIM 605936; gene; . neXtProt NX_Q9UBW5; -; . PharmGKB PA25356; -; . eggNOG ENOG410ITR5; Eukaryota; . eggNOG ENOG410Y56Y; LUCA; . HOGENOM HOG000252987; -; . HOVERGEN HBG004224; -; . InParanoid Q9UBW5; -; . KO K20119; -; . PhylomeDB Q9UBW5; -; . TreeFam TF313542; -; . Reactome R-HSA-6798695; Neutrophil degranulation; . ChiTaRS BIN2; human; . GenomeRNAi 51411; -; . PRO PR:Q9UBW5; -; . Proteomes UP000005640; Unplaced; . Bgee ENSG00000110934; -; . CleanEx HS_BIN2; -; . GO GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell; . GO GO:0030054; C:cell junction; IEA:UniProtKB-KW; . GO GO:0042995; C:cell projection; IEA:UniProtKB-KW; . GO GO:0005576; C:extracellular region; TAS:Reactome; . GO GO:1904813; C:ficolin-1-rich granule lumen; TAS:Reactome; . GO GO:0001891; C:phagocytic cup; IEA:UniProtKB-SubCell; . GO GO:0002102; C:podosome; IDA:UniProtKB; . GO GO:0034774; C:secretory granule lumen; TAS:Reactome; . GO GO:0005543; F:phospholipid binding; IDA:UniProtKB; . GO GO:0060326; P:cell chemotaxis; IMP:UniProtKB; . GO GO:0043312; P:neutrophil degranulation; TAS:Reactome; . GO GO:0006911; P:phagocytosis; engulfment; IMP:UniProtKB GO GO:0097320; P:plasma membrane tubulation; IDA:UniProtKB; . GO GO:0071800; P:podosome assembly; IMP:UniProtKB; . Gene3D 1.20.1270.60; -; 1; . InterPro IPR027267; AH/BAR-dom; . InterPro IPR003005; Amphiphysin; . InterPro IPR004148; BAR_dom; . Pfam PF03114; BAR; 1; . PRINTS PR01251; AMPHIPHYSIN; . SMART SM00721; BAR; 1; . PROSITE PS51021; BAR; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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